I always say 'Knocked Up' opened the doors, and 'Hangover' just burst it wide open. To this day, it's still surreal. And my wife's a doctor. All our friends are doctors - our close friends. And it's just that I have an odd job now. I think I'm like a doctor who had a detour, and I just have an odd job.
I never let on I was a comedian. I never acted out. It was really important to me, like, to not be Patch Adams. I was so super serious as a doctor, I would bark orders to my nurses. I was hard-core. I wanted to make sure I did my job right. I was perfectly trained to be a physician. You know, it wasn't a fluke. I worked hard at it.
During the day, I was a doctor. At night, you know, I was a comic. And it was really just to let off some steam. It just became my golf, you know, in many ways. Most doctors have golf as a hobby. Mine was doing comedy.
There's really no substitute for working hard. I think that's my biggest talent. There are always people who are funnier and more talented than I am, but I don't take anything for granted and I commit myself 100% to each of my roles.
I really realize the more movies I do just how important - it's so cliche when people say it, because everybody says it nowadays - but it's so important to keep it grounded. I totally understand what that means.
When I finished my residency in New Orleans, I went to L.A. where I would work as a doctor during the day, and then at night I would actually go to The Improv and do standup, all the while kind of cultivating my comedy resume.
I think critics tend to think that comedy is freakin' math. Like, this is the Pythagorean Theorem. They're not sophisticated enough to know that comedy is fluid, that it evolves, and these organic evolutions are what you have to embrace.
There is something special and different about being a father to twin daughters.
Medicine really matured me as a person because, as a physician, you're obviously dealing with life and death issues, issues much more serious than what we're talking about in entertainment. You can't get more serious than life and death. And if you can handle that, you can handle anything.